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Company

Exxel Pharma is a privately held pharmaceutical company dedicated to developing novel therapeutics for the treatment of neuronal hypersensitivity disorders. The Company’s lead program, EX937, is an oral, first-in-class, proprietary small molecule designed to specifically and peripherally inhibit the fatty acid amide hydrolase (FAAH) enzyme. Exxel plans to launch a first-in-human Phase 1/1b study of EX937 for the treatment of refractory chronic cough, a large underserved market with no current FDA-approved therapies. In preclinical studies, EX937 was found to be effective in multiple models of chronic cough. Additionally, EX937 has a favorable safety profile and, being entirely excluded from the brain, has negligible central side effect liability.  EX937 also has the potential to be utilized across a number of high-value indications, including migraine headache, painful peripheral neuropathies (e.g., caused by cancer chemotherapy) and hyperactive bladder. In addition to EX937, Exxel Pharma is advancing a second program focused on novel global FAAH inhibitors and targeting Social Anxiety and Autism Spectrum Disorder.